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Friday 26 April 2019
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Topic: Latest News

April 25, 2019
Haemophilia is an X-linked genetic disorder characterised by a deficiency or absence of coagulation factors VIII or IX, resulting in a life-long bleeding disorder

Haemophilia is an X-linked genetic disorder characterised by a deficiency or absence of coagulation factors VIII or IX, resulting in a life-long bleeding disorder.1–7 Haemophilia is also called the ‘Royal disease’ because Queen Victoria was a carrier of haemophilia and her descendants spread the disease among Royal houses throughout Europe.1
 
Types of haemophilia
 
The most common types of haemophilia are:
 

April 25, 2019
This major breakthrough and world-first could hail a new era in the design and production of new antibiotics and anticancer agents
After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex 'anti-tumour antibiotic' known to be highly effective against cancer cells as well as drug-resistant bacteria, and have reproduced it synthetically in the lab for the first time.
 
April 23, 2019
Scientists from the Cancer Research UK Manchester Institute at The University of Manchester showed that a small volume of blood can contain up-to-date genetic information about a patient's cancer to inform treatment choices

Scientists could help match cancer patients with no other treatment options to clinical trials with experimental medicines, by analysing the genetic faults in a sample of their blood, according to research published in Nature Medicine.
 

April 18, 2019
The Welsh Government will invest £3.6m in 2020/21 to attract and train more pharmacists in Wales, it announced yesterday

The Welsh Government will invest £3.6m in 2020/21 to attract and train more pharmacists in Wales, it announced yesterday (17 April).

April 16, 2019
Standardisation of doses of intravenous chemotherapy agents was initially proposed to improve pharmacy capacity and reduce medication errors and wastage; however, further optimisation of the administration of anticancer drugs can potentially contribute to a more efficient oncology unit

Key points
 
• Dose standardisation can reduce the risk of calculation errors, decrease preparation time, and reduce waste.
 
• Pharmacists play a critical role in the preparation of chemotherapy and the verification of prescriptions.
 
• An analysis of prescriptions by BOPA identified 2.3% errors that could result in patient harm.
 

April 16, 2019
The General Pharmaceutical Council (GPhC) is cracking down on internet pharmacy safety by making these businesses carry out identity checks on patients before they sell them medication

The General Pharmaceutical Council (GPhC) is cracking down on internet pharmacy safety by making these businesses carry out identity checks on patient

April 15, 2019
Equashield’s expansion to the UK highlights the company’s commitment to increasing safety measures for hazardous drug handlers across the globe
Equashield, a leading provider of closed system transfer devices (CSTDs) for hazardous drugs, has announced an expansion of its exclusive partnership with Leaf Medical Ltd to distribute its manual and automated CSTD solutions for the safe compounding and administration of hazardous drugs.
 
April 15, 2019
This collaboration is expected to take several forms, including joint design and implementation of clinical research, working meetings at scientific conferences, cross-entity working groups with diverse functional group participation and clinical trial innovations
The US-based Antibacterial Resistance Leadership Group (ARLG), part of the Duke Clinical Research Institute (DCRI) and the University Medical Center (UMC) Utrecht, the managing entity of the COMBACTE (Combatting Bacterial Resistance in Europe) consortium, will work together to solidify a comprehensive global community to combat the threat of antibiotic resistance around the world.
 
April 12, 2019
Research conducted at the School of Pharmacy and Pharmaceutical Sciences at Cardiff University, UK aimed to understand the development of bacterial resistance to four different topical antibiotics commonly used in some OTC sore throat medicines
Research presented at the 2019 European Congress of Clinical Microbiology & Infectious Diseases shows that the inappropriate of use of antibiotics legitimately available in over-the-counter (OTC) throat medications could be contributing to antibiotic resistance, thereby going against World Health Organization (WHO) goals.
 
April 12, 2019
Improving results for patients by realising the transformational potential of Real World Data
HONEUR (Haematology Outcomes Network in Europe) is a Janssen-led initiative and part of the company’s overall commitment to creating better outcomes for patients – in this case, by harnessing the full potential of Real World Data and the insights it can provide. 
 
April 10, 2019
In oncology, in particular, where there are often no alternatives to these medicines, shortages pose a threat to patient safety as they reduce adherence to therapy and limit the ability of physicians to provide effective treatment regimens

Shortages of essential cancer medicines have a direct impact on patient care across Europe.
 

To ensure that this issue remains a top priority on the EU policy agenda, ESMO collaborated with the European Parliament to organise a cross-partisan event entitled “Shortages of Inexpensive, Essential Medicines: Calling for Tangible Political Commitments in the EU”.1
 

April 10, 2019
Pharmacists who qualified in the European Union (EU) can continue to practise in the UK after Brexit, even in a no-deal scenario, the Government has confirmed.

Pharmacists who qualified in the European Union (EU) can continue to practise in the UK after Brexit, even in a no-deal scenario, the Government has c

April 10, 2019
Modelling study shows that up to 43% of the world’s future hepatitis C infections could be prevented if transmission among people who inject drugs was reduced

Stepping up efforts to prevent transmission of hepatitis C among people who inject drugs, could reduce future infections by 43% globally, according to a study by researchers at the University of Bristol published in the Lancet Gastroenterology and Hepatology.1
 

April 10, 2019
First PARP inhibitor approved in the EU for patients with this difficult-to-treat disease and third EU approval for Lynparza

The European Commission has approved Lynparza (olaparib) as a monotherapy for the treatment of adult patients with germline BRCA1/2-mutations (gBRCAm), and who have human epidermal growth factor receptor 2 (HER2)-negative locally-advanced or metastatic breast cancer.
 

April 9, 2019
NHS England has said it is going to ‘formally request’ that the Government bans GPs from prescribing homeopathy.

NHS England has said it is going to "formally request" that the Government bans GPs from prescribing homeopathy.

April 9, 2019
Cytokines, particularly interleukin-17 (IL-17) and IL-23, appear to play a pivotal role in the development of psoriasis and much effort has been placed on the development of drugs, such as tildrakizumab, that specifically target them

Key points
 
• Psoriasis affects between 2% and 4% of the population in Westernised countries.
 
• Psoriasis is now recognised as an immune-mediated inflammatory disease.
 
• Current therapies for those with moderate to severe disease focus on targeting cytokines, in particular IL-17, IL12 and IL-23.
 

April 9, 2019
A Northern Irish ‘ward pharmacist’ model is helping to reduce medication errors when patients are admitted to or discharged from hospital.

A Northern Irish ‘ward pharmacist’ model is helping to reduce medication errors when patients are admitted to or discharged from hospital.
 
The model involves fully integrating pharmacists and pharmacy technicians with other health professionals within a ward team.
 

April 8, 2019
Pharmacists are being asked to share their views on draft guidance for pharmacist independent prescribers, which has been issued by the General Pharmaceutical Council (GPhC).

Pharmacists are being asked to share their views on draft guidance for pharmacist independent prescribers, which has been issued by the Gen

April 8, 2019
A clinical review published in the BMJ provides new interim advice for doctors and clinicians in prescribing cannabis-based products and cannabinoids to treat certain conditions
Since a policy change in November 2018, specialist doctors registered with the General Medical Council (GMC), have been permitted to prescribe new medicines which derive from cannabis. Yet, research into these products has, to date, been limited creating an 'information vacuum' about these medicines, their benefits or harms.
 
April 5, 2019
Immediate first-line access to this combination could be a treatment option for up to 1700 advanced kidney cancer patients in England
Bristol-Myers Squibb has announced that the National Institute for Health and Care Excellence (NICE) has issued a Final Appraisal Determination recommending the combination of Opdivo® (nivolumab) plus Yervoy® (ipilimumab) to treat NHS patients in England with renal cell carcinoma (RCC). 
 
April 2, 2019
A pharmacist has been appointed onto a forum of healthcare professionals overseeing the delivery of the NHS Long-Term Plan (LTP).

A pharmacist has been appointed onto a forum of healthcare professionals overseeing the delivery of the

April 1, 2019
The Government’s medicines watchdog has issued guidance on fluoroquinolone antibiotics following some reports of ‘potentially irreversible’ side effects affecting multiple systems, organ classes and senses.

The Government’s medicines watchdog has issued guidance on fluoroquinolone antibiotics following some reports of ‘potentially irreversible’ side effects affecting multiple systems, organ classes and senses.
 
The Medicines and Healthcare Regulatory Authority (MHRA) cautioned healthcare professionals on 21 March against prescribing the drug and to advise patients to stop taking it if they experienced side effects including muscle pain and peripheral neuropathy.
 

March 28, 2019
New immunotherapy drug targets for cancer will be progressed through a multimillion-pound drug discovery alliance between Cancer Research UK, LifeArc and Ono Pharmaceutical Co Ltd
A multi-year partnership brings together Cancer Research UK’s network of world-leading scientists and drug discovery expertise, LifeArc’s renowned therapeutic antibody engineering and development expertise, and Ono’s considerable track record in developing cancer immunotherapies.
 
March 28, 2019
GPs have seen a significant increase in the number of patients requesting medicinal cannabis, according to new research.

GPs have seen a significant increase in the number of patients requesting medicinal cannabis, according to new research.

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