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LEADER
Tuesday 3 April 2012
The 40th anniversary of the EAHP represents a landmark in European hospital pharmacy that will be marked by the annual scientific congress
CONFERENCE MEETING REPORTS
Tuesday 3 April 2012
Antimicrobial stewardship and research into the frequency, nature and causes of prescribing errors were key topics at the UKCPA Autumn Symposium
CONFERENCE MEETING REPORTS
Tuesday 3 April 2012
Safe handling of cytotoxic agents, occupational exposure and drug vial optimisation were key topics at a recent satellite symposium sponsored by Becton-Dickinson
OPINION
Tuesday 3 April 2012
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
With the European patent expiration of calcineurin inhibitors, it is important that pharmacists understand the generic approval process and the interpretation of bioequivalence testing
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
Since the success of biologics in the treatment of rheumatoid arthritis, much attention has focused on the development of small molecule inhibitors as a cost-effective and orally available alternative. Here, the progress of the most recent SMI candidates undergoing clinical trials in RA is discussed
BIOSIMILARS
Tuesday 3 April 2012
As the population is ageing and cancer incidence is rising, healthcare professionals and patients will be faced with financial constraints when it comes to delivering expensive cancer care. Biosimilars could be part of the solution
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
This article reviews the health economic evidence relating to antiretroviral protease inhibitors and protease inhibitors used in hepatitis C, and draws attention to the cost-effectiveness of telaprevir
INTERVIEW
Tuesday 3 April 2012
Following active research in the 1990s, the last decade has seen two notable advances in antipsychotic development. Psychopharmacology expert Professor David Taylor discusses this progress, with a focus on the latest addition to the group
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
With few antimicrobial agents for serious gram-positive infections available, the need for alternatives to vancomycin, such as the lipoglycopeptide, telavancin, is clear
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
There is no specific treatment currently recommended for the prevention of acute kidney dysfunction. This review will focus on the risk
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
At each stage of the medicines use pathway, pharmacists are ideally placed to intervene to optimise drug use and limit the opportunities for problematic, resistant bacteria to cause catheter-related bloodstream infections
DRUG EVALUATION
Tuesday 3 April 2012
Oral methotrexate is a well-established treatment in rheumatoid arthritis. Failure of oral methotrexate is often due to poor absorption or intolerance as a result of gastrointestinal side effects. Subcutaneous methotrexate may overcome these problems and offers an alternative before escalation to a biologic. This paper examines the pharmacoeconomic impact of using subcutaneous methotrexate as an alternative to biologic therapy in patients who have failed, or are intolerant of, oral methotrexate. The analysis was based on the UK population and factored in incidence rates for rheumatoid arthritis, methotrexate and biologic failure rates, as well as drug and monitoring costs.
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
The management of advanced renal cell carcinoma (RCC) has changed dramatically over the last decade. With a plethora of targeted drugs to choose from, the major challenge is to minimise treatment-related toxicity
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
Rebif is the only self-injected relapsing multiple sclerosis therapy that meets the treatment goals of slowing disability progression, reducing relapse rate and reducing the development of brain lesions
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
The most common injection side-effects in patients receiving subcutaneous azacitidine for myelodysplastic syndromes are febrile neutropaenia, anaemia and infections, but these are also symptoms of the disease itself
PHARMACEUTICAL TECHNOLOGY
Tuesday 3 April 2012
Sterility and operator safety are key features of the CareFusion closed system device
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
The lack of licensing in children of sedative medicines has led to a wide scope of practice. Medicines are not formulated to be suitable for children (for example, high strength, no masking of taste) and pose an additional risk for patients
PRACTICAL THERAPEUTICS
Tuesday 3 April 2012
Abiraterone acetate is a groundbreaking development for castration-resistant prostate cancer, an aggressive and lethal condition
VANTAGE POINT
Tuesday 3 April 2012
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